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Dihexa is a synthetic peptide derived from Angiotensin IV, engineered to cross the blood-brain barrier and activate the HGF/c-Met pathway — a primary driver of synaptogenesis and new neural connection growth. Researchers
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Small Molecule AngIV-based Analogs to Treat Alzheimers Disease
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The HGF/c-Met signaling axis. After HGF binding to the c-Met receptor
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Monoclonal Antibodies against the MET/HGF Receptor and Its Ligand: Multitask Tools with Applications from Basic Research to Therapy
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Hepatocyte Growth Factor/MET Activator Rescues Working Memory Deficits after Repeated Mild Traumatic Brain Injury
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Dihexa (also known as PNB-0408) is an experimental small molecule derived from angiotensin IV. It was engineered to cross the blood–brain barrier and has shown synaptogenic effects in preclinical models. The often-quoted
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The Therapeutic Targeting of HGF/c-Met Signaling in Hepatocellular Carcinoma: Alternative Approaches
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