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nauseous on tirzepatide GLP-1 nausea: How to handle GLP-1s' most common side effect

Marsoni M251S
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4.4 ★★★★★
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Average Guy
Phoenix, US
★★★★★ 3
KIND OF BAGGY
Size: Large, Color: A-multicolored-4 Pack
I guess I'm not built quite like the guy in the photo. I found these to be a little baggy. I buy briefs because I don't want baggy. They were, however, comfortable enough. I liked the wider waist band and the elastic was fine. I wouldn't buy them again though.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on July 27, 2024
A
Verified Purchase
Arshad
Battle Creek, US
★★★★★ 5
Decent Quality
Size: Medium, Color: Black, Navy Blue, Brown, Heather Grey-4 Pack
as per website. decent quality
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Reviewed in the United States on May 31, 2026
D
Verified Purchase
Daryl Johnston
Dallas, US
★★★★★ 5
Comfortable and secure
Size: Small, Color: Black Grey
Nice quality non fly men’s underwear. Pouch holds your gear firmly. Ordered small (30” waist) but ended up ordering same item in medium for more comfort. Also went with the cotton version.
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Reviewed in the United States on November 7, 2025
M
Verified Purchase
Morstead
Los Angeles, US
★★★★★ 5
Comfortable & well-fitting, but some differences in stiffness between batches
Size: Medium, Color: Black/Deep Blue/Deep Grey/Heather Grey
I've basically been exclusively buying these since I've discovered them. Super-comfortable and maintain their shape for a long time, but I've noticed from buying it multiple times that sometimes the pouch area has stiffer texture and more support than other times (when it's loose & stretchy like the rest of it). I wish I could specify receiving the more-supported ones because they tend to produce less....how to say, knocking the boys around.
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Reviewed in the United States on March 22, 2026
E
Verified Purchase
EclecticJay
Belleville, US
★★★★★ 5
Comfort and softness
Size: 3X-Large, Color: Black/Navy/Dark Grey/Red
True to size; they are comfortable, good quality, and really soft.
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Reviewed in the United States on January 3, 2026

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