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tirzepatide egfr cut-off Tirzepatide (Zepbound) showed improved kidney function in obese patients with both chronic kidney disease and #heartfailure with preserved ejection fraction, highlighting its potential to address this high-risk patient population. Read more: https

Marsoni M251S
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4.1 ★★★★★
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Julie
Waukegan, US
★★★★★ 4
Small, but twisty and fun looking. Seems relatively sturdy, though doesn't look indestructible at all.
Color: Rubber Chew Toy, Size: Large
SLIGHTLY disappointed because I thought this was bigger than it is. If you squish it all in close, it's maybe one and a half times the size of a tennis ball. (Of course, the size is probably listed; I think I just assumed, so my fault.) That being said, it's entertainingly twisty and squishy, though the rubber seems relatively sturdy. I'm not yet positive if it will hold up to the 8 month retriever/lab mix it's intended for; he tends to rip instantly through anything much less sturdy than kong natural rubber. But it seems like something that will amuse him, so we're going to give it a shot at Christmas.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on November 7, 2014
K
Verified Purchase
Kindle Customer
Lexington, US
★★★★★ 5
Great product!
Color: Rubber Chew Toy, Size: Large
My dog is an aggressive chewer. I have bought this 3 times for her she loves to play tug and fetch with it. They last longer than most of the other toys I get her and it’s one of her favorites.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on January 1, 2025
K
Verified Purchase
Kate
Dallas, US
★★★★★ 3
It’s okay I guess
Color: Rubber Chew Toy, Size: Large
Good price and decent toy, seems well made. My puppy is entirely uninterested and doesn’t play with it at all.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on April 23, 2026
P
Verified Purchase
PattyJoyce on Joe List
Port Orchard, US
★★★★★ 1
Very dangerous for chewers!!!
Color: Rubber Chew Toy, Size: Large
My dog was chewing/swallowing the hard rubber within seconds of having this "toy"!!! Not safe, sturdy, no play attraction; only desire was to consume!!!
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Reviewed in the United States on March 16, 2026
A
Verified Purchase
Amazon Customer
Cuba, US
★★★★★ 5
Get one!
Color: Rubber Chew Toy, Size: Large, Color: Rubber Chew Toy, Size: Large
This was my puppy’s fav toy for the longest time. Not too heavy and is the right amount of tough for a chewing teething puppy. Cute toy that’s easy to chew and safe for a teething puppy it’s not loud and lasts. Worth the price.
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Reviewed in the United States on November 14, 2025

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